dh-virtualenv
dh-virtualenv is a tool that aims to combine Debian packaging with self-contained virtualenv based Python deployments.
The idea behind the dh-virtualenv is to be able to combine power of Debian packaging with the sandboxed nature of virtualenvs. In addition to this, using virtualenv enables installing requirements via Python Package Index instead of relying on the operating system provided Python packages. The only limiting factor is that you have to run the same Python interpreter as the operating system.